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# Denotes co-first author, *Denotes corresponding author

2024

 

26. Gao, J.*, Xia, Z., Gunasekar, S. et al. Precision drug delivery to the central nervous system using engineered nanoparticles. Nat Rev Mater (2024). https://doi.org/10.1038/s41578-024-00695-w

 

25. Gao, J.*, Gunasekar, S., Xia, Z.. et al. Gene therapy for CNS disorders: modalities, delivery and translational challenges. Nat. Rev. Neurosci. (2024). https://doi.org/10.1038/s41583-024-00829-7

24. Li, Xinyan#, Jingjing Gao#, Chengcheng Wu, Chaoyu Wang, Ruoshi Zhang, Jia He, Ziting Judy Xia, Nitin Joshi, Jeffrey M. Karp, and Rui Kuai. Precise modulation and use of reactive oxygen species for immunotherapy. Science Advances 10, no. 20 (2024): eadl0479. 

2023

23. Wu, R., Prachyathipsakul, T., Zhuang, J., Liu, H., Han, Y., Liu, B., Gao,J. Xiao, H., Thayumanavan, S. Conferring liver selectivity to a thyromimetic using a novel nanoparticle increases therapeutic efficacy in a diet-induced obesity animal model. PNAS Nexus, 2023. 2(8).

22. Huynh, U.; Wu, P.; Qiu, J.; Prachyathipsakul, T.; Singh, K.; Jerry, D. J.; Gao, J.*; Thayumanavan, S*. Targeted Drug Delivery Using a Plug-to-Direct Antibody–Nanogel Conjugate. Biomacromolecules 2023, 24 (2), 849–857. https://doi.org/10.1021/acs.biomac.2c01269. 

21. Liu, H.-J., Chen, W., Wu, G., Zhou, J., Liu, C., Tang, Z., Huang, X., Gao, J., Xiao, Y., Kong, N., Joshi, N., Cao, Y., Abdi, R., Tao, W., Glutathione-Scavenging Nanoparticle-Mediated PROTACs Delivery for Targeted Protein Degradation and Amplified Antitumor Effects. Adv. Sci. 2023, 10, 2207439. 

20. Gao, J.; Karp, M.J.; Langer, R.; Joshi, N. The future of drug delivery. Chemistry of Materials, 2023, 35 (2), 359-363.

 

2022

19. Gao, J.; Xia, Z.; Joseph, J.; Luo, J.; Joshi, N. Progress in non-viral localized delivery of siRNA therapeutics for pulmonary diseases. Acta Pharmaceutica Sinica B, 2022, https://doi.org/10.1016/j.apsb.2022.07.010.

18. Joseph, J., Baby, H.M., Zhao, S., Li, X.L., Cheung, K.C., Swain, K., Agus, E., Ranganathan, S., Gao, J., Luo, J.N. and Joshi, N., Role of bioaerosol in virus transmission and material‐based countermeasures. Exploration, 2022, 20210038.

17. Gao, J.; Xia, Z.; Mary, H.; Joseph, J.; Luo, J.; Joshi, N. Overcoming barriers for intra-articular delivery of disease-modifying osteoarthritis drugs. Trends Pharmacol. Sci. 2022, 43(3), 171-187. [Featured as front cover]

2021

16. Gao, J.; Prachyathipsakul, T.; Thayumanavan, S. Multichannel dual protein sensing using amphiphilic supramolecular assemblies. Chem Commun, 2021, 57, 12828-12831.

15. Wu, P.; Gao, J.; Prasad, P.; Dutta, K.; Kanjilal, P.; Thayumanavan, S. Influence of Polymer Structure and Architecture on Drug Loading and Redox-Triggered Release. Biomacromolecules. 2022, 23, 339-348.

14. Gao, J.; Le, S., Thayumanavan, S. Enzyme Catalysis in Non‐native Environment with Unnatural Selectivity Using Polymeric Nanoreactors. Angewandte Chemie International Edition, 2021, 60 (52), 27189-27194.

13. Cao, R.#, Gao, J.#, Thayumanavan, S., Dinsmore, T. Triggerable interactions between membrane and nanoparticle: from adhesion to disruption. Soft. Matter. 2021, 17, 7069-7075.

12. Nandi, D., Shivrayan, M., Gao, J., Krishna, J., Das, R., Liu, B., Thayumanavan, S. and Kulkarni, A., 2021. Core Hydrophobicity of Supramolecular Nanoparticles Induces NLRP3 Inflammasome Activation. ACS Appl. Mater. Interfaces 2021, 13, 38, 45300–45314.

2020

11. Gao, J.; Dutta, K.; Zhuang, J.; Thayumanavan, S. Cellular and subcellular targeted delivery using a simple all-in-one polymeric nanoassemblies. Angew. Chem. Int. Ed. 2020, 132, 23672-23676.

10. Gao, J.; Wu, P., Fernandez, A, Zhuang, J.; Thayumanavan, S. Cellular AND gates synergize to boost selective uptake of polymeric assemblies. Angew. Chem. Int. Ed. 2020, 59, 10456-10460.

9. Zhao, B.; Gao, J.; Thayumanavan, S.; Vachet, R. W. Polymeric Nanoassemblies for Enrichment and Detection of Peptides and Proteins in Human Breast Milk. Anal. Bioanal. Chem, 2020, 412, 1027-1035.

2019

8. Wang, M.; Gao, J.; Zhang, X.; Zhao, B.; Thayumanavan, S.; Vachet, R. W. Efficient enrichment of glycopeptides by supramolecular nanoassemblies that use proximity-assisted covalent binding. Analyst, 2019, 144, 6321-6326.

7. Gao, J.; Wang, Hui.; Zhuang, J.; Thayumanavan, S. Tunable enzyme responses in amphiphilic nanoassemblies through alterations in unimer-aggregate equilibrium. Chem. Sci.,2019, 10, 3018-3024.

2015-2018

6. Gao, J.; Zhao, B.; Wang, M.; Serrano, M. A. C.; Zhuang, J.; Ray, M.; Rotello, V.; Vachet, R. W.; Thayumanavan, S. Supramolecular Assemblies for Transporting Proteins Across an Immiscible Solvent Interface. J. Am. Chem. Soc., 2018, 140, 2421–2425.

5. Serrano, M. A. C.; Gao, J.; Thayumanavan, S.; Vachet, R. W. Supramolecular Polymeric Assemblies for the Selective Depletion of Abundant Acidic Proteins in Serum. ACS Appl. Mater. Interfaces, 2018, 10, 40443–40451.

4. Gao, J.; Liu, X.; Secinti, H.; Jiang, Z.; Munkhbat, O.; Xu, Y.; Guo, X.; Thayumanavan, S. Photoactivation of Ligands for Extrinsically and Intrinsically Triggered Disassembly of Amphiphilic Nanoassemblies. Chem. Eur. J. 2018, 24, 1789-1794.

3. Zhao, B.; Serrano, M. A. C.; Gao, J.; Zhuang, J.; Vachet, R. W.; Thayumanavan, S. Self-assembly of Random Co-polymers for Selective Binding and Detection of Peptides. Polym. Chem. 2018, 9, 1066-1071.  [Featured as front cover]

2. Wang, M.; Zhao, B.; Gao, J.; He, H.; Castellanos, L. J.; Thayumanavan, S.; Vachet, R. W. Altering the Peptide Binding Selectivity of Polymeric Reverse Micelle Assemblies via Metal Ion Loading. Langmuir, 2017, 33, 14004–14010. [Featured as front cover]

1. Gao, J.; Luo, X.; Li, Y.; Gao, R.; Chen, H; and Ji, D. Synthesis and Biological Evaluation of 2-oxo-pyrazine-3-carboxamide-yl Nucleoside Analogues and Their Epimers as Inhibitors of Influenza A Viruses. Chem. Biol. Drug. Des, 2015, 85, 245–252. [Featured as front cover]

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